News
Latest updates from the Netherlands Cancer Institute in Artificial Intelligence

STAPLER: a language model to predict TCR–pMHC reactivity
Our latest paper introduces STAPLER, a cutting-edge language model that significantly enhances TCR-pMHC reactivity prediction, outperforming previous models in the field.
A deeper understanding of TCR-pMHC interactions is key to unlocking the potential of personalized immunotherapies and expanding our knowledge of the immune system.
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GPU cluster expanded with gaia and galileo
We have added another 8xA6000 server (galileo) and a CPU server (gaia) to our Kosmos cluster. Kosmos now consists out of 70 GPUs, more than 1100 CPU cores, 6TB RAM and 1PB NAS.
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Retrospective k-space Subsampling schemes For Deep MRI Reconstruction
In our new publication, we investigate and compare various retrospective k-space subsampling patterns and their effect on the quality of DL-based reconstructions. Our findings suggest that non-rectilinear and non-Cartesian subsampling patterns may be more suitable for DL-based reconstructions.
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New A100 80GB server installed
Another compute node has been installed in the AI for Oncology Cluster kosmos. The server, nicknamed euctemon, consists of 8xA100 80G, dual CPU and 1TB of memory. Euctemon joins the slurm cluster which now consists out of 16xA100 80GB, 16xA6000 48GB and 4x RTX2080Ti, and 1 PB NAS.
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Application of Deep Learning in Breast Cancer Imaging
Luuk Balkenende has published the first paper of his PhD in Seminars in Nuclear Medicine on "Applications of Deep Learning in Breast Cancer Imaging" where he reviews the current usages of deep learning for mammography, ultrasound and breast MRI.
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Our RecurrentVarNet wins the Multi-Coil MRI Reconstruction Challenge
The Recurrent Variational Network was ranked as the top method in the Multi-Coil MRI Reconstruction (MC-MRI) Challenge. The corresponding paper which assessed the generalizability of brain MRI Reconstruction models to varying coil configurations was published in the Frontiers in Neuroinformatics.
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Recurrent Variational Network presented at CVPR
Our paper "Recurrent Variational Network: A Deep Learning Inverse Problem Solver applied to the task of Accelerated MRI Reconstruction" has been accepted for publication at CVPR 2022! CVPR is the top ranked Computer Science conference with leading h5-index and impact score! Our work proposes a novel DL Inverse Problem solver, the RecurrentVarNet, employed and evaluated in the essential task of Accelerated MRI Reconstruction achieving SOTA results!
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Open-source Deep MRI Reconstruction software published
Our open-source Deep Image REConstruction Toolkit (DIRECT) has been accepted for publication in the Journal of Open Source Software (JOSS)! DIRECT stores multiple DL model baselines such as the Recurrent Variational Network, implemented in PyTorch for end-to-end Accelerated MRI Reconstruction tasks and allows for use with datasets such as the fastMRI and Calgary Campinas Datasets!
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DeepSMILE published in Medical Image Analysis
In this work we use whole-slide image (WSI) compression and multiple instance learning to predict homologous recombination deficiency and microsatellite instability from breast cancer and colorectal cancer WSIs. Both these labels are closely related to a patient’s response to immune- and targeted therapies.
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